Advice
NICE is unable to make a recommendation about the use in the NHS of methylnaltrexone bromide for treating opioid-induced constipation. This is because Swedish Orphan Biovitrum Ltd did not provide an evidence submission.
Information
If NHS organisations wish to consider methylnaltrexone bromide for treating opioid-induced constipation, they should follow the advice on rational local decision-making in the NHS Constitution for England and the NHS Commissioning Board and Clinical Commissioning Groups (Responsibilities and Standing Rules) Regulations 2012. This outlines the approach that should be taken when there is no NICE guidance.
NICE will review the position if the company decides that it wants to make an evidence submission.
ISBN: 978-1-4731-2645-9