Palbociclib with an aromatase inhibitor for previously untreated, hormone receptor-positive, HER2-negative, locally advanced or metastatic breast cancer

Final appraisal determination: 1

Final appraisal determination document (PDF 442 KB)

Public committee slides ACM3 (PDF 644 KB)

Public committee slides ACM2 (PDF 606 KB)

Committee papers Equality Impact Assessment Form (PDF 235 KB)

Committee papers (PDF 6.13 MB)

Draft guidance

Appraisal consultation document (PDF 424 KB)

Committee papers (PDF 24.04 MB)

Committee papers Clinical and Cost Effectiveness Presentation Slides (PDF 1.39 MB)

Final scope (PDF 114 KB)

Final matrix (PDF 100 KB)

NICE's response to comments on the draft scope and provisional matrix (PDF 215 KB)

Equality impact assessment (Scoping) (PDF 64 KB)

Draft scope (pre-referral) (PDF 132 KB)

Provisional matrix (pre-referral) (PDF 102 KB)