Nivolumab for adjuvant treatment of completely resected melanoma with lymph node involvement or metastatic disease

2.1 Nivolumab (Opdivo, Bristol-Myers Squibb) is indicated as monotherapy for 'the adjuvant treatment of adult patients with melanoma with involvement of lymph nodes or metastatic disease who have undergone complete resection'.

2.2 The dosage schedule is available in the summary of product characteristics.

2.3 The list price is £439 per 40 mg/4 ml concentrate for solution for infusion vial; £1,097 per 100 mg/10 ml concentrate for solution for infusion vial; and £2,633 per 240 mg/24 ml concentrate for solution for infusion vial (excluding VAT; BNF online, accessed October 2020).

2.4 The company has a commercial arrangement. This makes nivolumab available to the NHS with a discount. The size of the discount is commercial in confidence. It is the company's responsibility to let relevant NHS organisations know details of the discount.