2 Information about burosumab

Marketing authorisation indication

2.1

Burosumab (Crysvita, Kyowa Kirin) is indicated for 'the treatment of X‑linked hypophosphataemia in children and adolescents aged 1 to 17 years with radiographic evidence of bone disease, and in adults'.

Dosage in the marketing authorisation

Price

2.3

The list prices per vial of solution for injection are £2,992 for 10 mg/1 ml, £5,984 for 20 mg/1 ml, and £8,976 for 30 mg/1 ml (excluding VAT; BNF online accessed November 2023).

2.4

The company has a commercial arrangement. This makes burosumab available to the NHS with a discount. The size of the discount is commercial in confidence.