Information for the public

Linzagolix (Yselty) is available on the NHS as a possible treatment for moderate to severe symptoms of uterine fibroids in adults of reproductive age. It is only available if it is used as a longer-term treatment (more than 6 months) in the following doses:

  • 200 mg is used once daily for adults having hormonal add-back therapy.
  • 200 mg is used once daily for 6 months and then reduced to 100 mg once daily for adults not having hormonal add-back therapy.

If you are not eligible for linzagolix but are already having it, you should be able to continue until you and your doctor decide when best to stop.

Is this treatment right for me?

Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns. Your family can be involved too, if you wish. See our webpage on making decisions about your care.

Questions to think about

  • How well does it work compared with other treatments?
  • What are the risks or side effects? How likely are they?
  • How will the treatment affect my day-to-day life?
  • What happens if the treatment does not work?
  • What happens if I do not want to have treatment? Are there other treatments available?

Information and support

The NHS webpage on fibroids may be a good place to find out more.

You can also get support from your local Healthwatch.

NICE is not responsible for the quality or accuracy of any information or advice provided by these organisations.

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