Single technology appraisal and highly specialised technologies evaluation: User guide for company evidence submission template

Identification of studies

Describe the strategies used to retrieve cost-effectiveness studies relevant to decision-making in England from published NICE technology evaluations, the published literature and from unpublished data held by the company. Justify the methods used with reference to the decision problem and the NICE reference case. Provide sufficient detail to enable the methods to be reproduced, and the rationale for any inclusion and exclusion criteria used.

Description of identified studies

Provide a brief overview of each cost-effectiveness study only if it is relevant to decision-making in England. Describe the aims, methods and results for each study. Each study's results should be interpreted with reference to a critical appraisal of its methodology. When studies have been identified and not included, justification for this should be provided. If more than 1 study is identified, please present the information in a table.

Critical appraisal of the identified studies

Provide a complete quality assessment for each relevant cost-effectiveness study identified. Use an appropriate and validated instrument, such as Drummond and Jefferson, guidelines for authors and peer reviewers of economic submissions to the BMJ (1996) or quality assessment in decision-analytic models: a suggested checklist (appendix 3) in Philips et al. Review of guidelines for good practice in decision-analytic modelling in health technology assessment (2004).

This section should be read with NICE's health technology evaluations manual, section 3.3.26 to 3.3.27.