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Single technology appraisal and highly specialised technologies evaluation: User guide for company evidence submission appendices

Appendix H: Health-related quality-of-life studies

Appendix H: Health-related quality-of-life studies

Describe how systematic searches for relevant health-related quality-of-life data were done. Consider published and unpublished studies, including any original research commissioned for the technology. Provide the rationale for terms used in the search strategy and any inclusion and exclusion criteria used. The search strategy used should be provided in the appendix.

Tabulate the details of the studies in which health-related quality of life was measured. Include the following, but note that this list is not exhaustive:

  • population in which health effects were measured

  • information on recruitment (for example, participants of a clinical trial, approximations from clinical experts, utility elicitation exercises including members of the general public or patients)

  • interventions and comparators

  • sample size

  • response rates

  • description of health states

  • adverse reactions

  • appropriateness of health states given the condition and treatment pathway

  • method of elicitation

  • method of valuation

  • mapping

  • uncertainty around values

  • consistency with reference case.


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