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Advice programme

Showing 5506 to 5520 of 7683 results

  1. Second-line maintenance therapy in children and young people (under 16):- Is maintenance therapy more effective with a paediatric low dose of ICS plus a leukotriene receptor antagonist (LTRA) or with a paediatric low dose of ICS plus a long-acting beta2 agonist (LABA) in the treatment of asthma in children and young people (under 16) who have uncontrolled asthma on a paediatric low dose of ICS alone?

    Recommendation ID NG80/7 Question Second-line maintenance therapy in children and young people (under 16):- Is maintenance therapy more

    Research recommendation
    Published
    18 October 2018

  2. SEM Scanner 200, with visual skin assessment, shows promise for preventing pressure ulcers. However, there is not enough good-quality evidence to support the case for routine adoption in the NHS. A randomised controlled trial is recommended to address uncertainties about the clinical benefits of using the scanner compared with standard risk assessment. This should assess: using the scanner plus visual skin assessment compared with visual skin assessment alone for identifying pressure ulcer risk whether changes in clinical decision making from using the scanner reduce pressure ulcer incidence the clinical benefits and resource impact of using the scanner in different care settings the clinical benefits for different skin tones how well the scanner works across populations with a range of comorbidities patient-related outcome measures.

    Recommendation ID MTG51/1 Question SEM Scanner 200, with visual skin assessment, shows promise for preventing pressure ulcers. However

    Research recommendation
    Published
    26 October 2020

  3. Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG tissue transglutaminase (tTG), IgG endomysial antibodies (EMA) and IgG deamidated gliadin peptide (DGP) tests in detecting coeliac disease in people with IgA deficiency?

    Recommendation ID NG20/1 Question Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG

    Research recommendation
    Published
    13 October 2015

  4. Research is needed to establish the efficacy and tolerability of bile acid sequestrants among people with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/3 Question Research is needed to establish the efficacy and tolerability of bile acid sequestrants among people with

    Research recommendation
    Published
    9 June 2015

  5. Research is recommended on HumiGard compared with standard insufflation gases in patients having laparoscopic or open surgery alongside general measures to reduce the risk of perioperative hypothermia (described in section 2.5). Research should report on the comparative rate of surgical site infections and other complications associated with hypothermia and normothermia, as well as related resource use.

    Recommendation ID MTG31/1 Question Research is recommended on HumiGard compared with standard insufflation gases in patients having laparoscopic

    Research recommendation
    Published
    26 April 2017

  6. Research is needed to establish the nature of bile acid malabsorption and whether bile acid malabsorption is a primary or secondary condition in people diagnosed with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/2 Question Research is needed to establish the nature of bile acid malabsorption and whether bile acid malabsorption

    Research recommendation
    Published
    9 June 2015

  7. Research is recommended on patient preferences, and their impact on quality of life, for contrast-enhanced ultrasound and other imaging modalities. Ideally such research should compare all appropriate imaging modalities in the same patient group.

    Recommendation ID DG5/2 Question Research is recommended on patient preferences, and their impact on quality of life, for contrast-enhanced

    Research recommendation
    Published
    9 June 2015

  8. Research is needed to establish the validity and accuracy of the SeHCAT (tauroselcholic [75selenium] acid) test and of any potential alternative technologies for measuring bile acid malabsorption in people with chronic diarrhoea diagnosed with irritable bowel syndrome (IBS-D) or Crohn's disease without ileal resection.

    Recommendation ID DG7/1 Question Research is needed to establish the validity and accuracy of the SeHCAT (tauroselcholic [75selenium] acid)

    Research recommendation
    Published
    9 June 2015

  9. Research is recommended on the percentage of unenhanced ultrasound scans that are inconclusive, particularly in people with cirrhosis. Such studies should explicitly define and describe why scans are 'inconclusive'.

    Recommendation ID DG5/1 Question Research is recommended on the percentage of unenhanced ultrasound scans that are inconclusive, particularly

    Research recommendation
    Published
    9 June 2015

  10. Research is recommended to address uncertainties about the claimed benefits of using Mepilex Border Heel and Sacrum dressings. This research should also explore issues such as:- the incidence of heel and sacrum pressure ulcers in NHS acute care settings- criteria for patient selection to reduce pressure ulcer incidence with Mepilex Border Heel and Sacrum dressings in addition to standard care.NICE will consider reviewing this guidance when substantive new evidence becomes available.

    Recommendation ID MTG40/1 Question Research is recommended to address uncertainties about the claimed benefits of using Mepilex Border

    Research recommendation
    Published
    7 March 2019

  11. Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's disease on both short-term and long-term outcomes, disease progression through relevant health states, and quality of life.

    Recommendation ID TA217/1 Question Research is needed to generate robust and relevant data on the effects of treating people with Alzheimer's

    Research recommendation
    Published
    9 June 2015

  12. Research is needed to quantify the health outcome benefits associated with imaging improvements with the EOS system. Examples of such benefits might include reduced back pain or reduced postural difficulties in people with scoliosis, or longer lasting and less painful joint replacements. Although research into the use of the EOS system is appropriate for all the indications included in the scope, the research most likely to be useful is for planning hip and knee replacement, including patient selection, device selection, and surgical approach. Joint replacement operations are more common than the other indications and the EOS system is thought to be most likely to provide benefit to these patients.

    Recommendation ID DG1/1 Question Research is needed to quantify the health outcome benefits associated with imaging improvements with the

    Research recommendation
    Published
    9 June 2015

  13. Research is recommended to address uncertainties about the claimed patient and system benefits of the ReCell Spray-On Skin system. Clinical outcomes should include time to 95% healing, length of hospital stay, cosmetic appearance of the scar and function of the burned area, compared with standard care.

    Recommendation ID MTG21/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of the

    Research recommendation
    Published
    9 June 2015

  14. Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination with cardiac troponin testing against sequential cardiac troponin testing for ruling out myocardial infarction.

    Recommendation ID MTG4/1 Question Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination

    Research recommendation
    Published
    9 June 2015

  15. Research is recommended to address uncertainties about the claimed patient and system benefits of using Parafricta Bootees and Undergarments.

    Recommendation ID MTG20/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of using

    Research recommendation
    Published
    10 August 2021