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Guidance programme

Advice programme

Showing 5611 to 5625 of 7679 results

  1. Second-line maintenance therapy in children and young people (under 16):- Is maintenance therapy more effective with a paediatric low dose of ICS plus a leukotriene receptor antagonist (LTRA) or with a paediatric low dose of ICS plus a long-acting beta2 agonist (LABA) in the treatment of asthma in children and young people (under 16) who have uncontrolled asthma on a paediatric low dose of ICS alone?

    Recommendation ID NG80/7 Question Second-line maintenance therapy in children and young people (under 16):- Is maintenance therapy more

    Research recommendation
    Published
    18 October 2018

  2. SEM Scanner 200, with visual skin assessment, shows promise for preventing pressure ulcers. However, there is not enough good-quality evidence to support the case for routine adoption in the NHS. A randomised controlled trial is recommended to address uncertainties about the clinical benefits of using the scanner compared with standard risk assessment. This should assess: using the scanner plus visual skin assessment compared with visual skin assessment alone for identifying pressure ulcer risk whether changes in clinical decision making from using the scanner reduce pressure ulcer incidence the clinical benefits and resource impact of using the scanner in different care settings the clinical benefits for different skin tones how well the scanner works across populations with a range of comorbidities patient-related outcome measures.

    Recommendation ID MTG51/1 Question SEM Scanner 200, with visual skin assessment, shows promise for preventing pressure ulcers. However

    Research recommendation
    Published
    26 October 2020

  3. Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG tissue transglutaminase (tTG), IgG endomysial antibodies (EMA) and IgG deamidated gliadin peptide (DGP) tests in detecting coeliac disease in people with IgA deficiency?

    Recommendation ID NG20/1 Question Serological testing in people who have IgA deficiency:- What is the sensitivity and specificity of IgG

    Research recommendation
    Published
    13 October 2015

  4. Serological testing in people who test negative for anti-transglutaminase:- What is the sensitivity and specificity of IgA EMA and IgA DGP tests in detecting coeliac disease inpeople who test negative for IgA tTG?

    Recommendation ID NG20/2 Question Serological testing in people who test negative for anti-transglutaminase:- What is the sensitivity and

    Research recommendation
    Published
    13 October 2015

  5. Safety and efficacy of antimuscarinics:- What is the safety and efficacy of more recently developed antimuscarinics compared with (a) placebo/usual care and (b) other antimuscarinics in the treatment of neurogenic lower urinary tract dysfunction?

    Recommendation ID CG148/1 Question Safety and efficacy of antimuscarinics:- What is the safety and efficacy of more recently developed

    Research recommendation
    Published
    9 June 2015

  6. Safety and efficacy of botulinum toxin:- What is the safety and efficacy of botulinum toxin compared with (a) usual care, (b) antimuscarinics and (c) augmentation cystoplasty in people with neurogenic lower urinary tract dysfunction?

    Recommendation ID CG148/2 Question Safety and efficacy of botulinum toxin:- What is the safety and efficacy of botulinum toxin compared

    Research recommendation
    Published
    9 June 2015

  7. Safety and safeguarding:- What safeguarding practices are most effective in improving outcomes for people using services?

    Recommendation ID NG21/5 Question Safety and safeguarding:- What safeguarding practices are most effective in improving outcomes for people

    Research recommendation
    Published
    13 October 2015

  8. Selective dorsal rhizotomy:- Does selective dorsal rhizotomy followed by intensive rehabilitation performed between the ages of 3 and 9 years in children who are at Gross Motor Function Classification System (GMFCS) level II or III result in good community mobility as a young adult?

    Recommendation ID CG145/5 Question Selective dorsal rhizotomy:- Does selective dorsal rhizotomy followed by intensive rehabilitation performed

    Research recommendation
    Published
    9 June 2015

  9. Selective internal radiation therapy for unresectable colorectal metastases in the liver

    Recommendation ID IPG672/1 Question Selective internal radiation therapy for unresectable colorectal metastases in the liver

    Research recommendation
    Published
    17 March 2020

  10. Saliva:- How is excessive drooling of saliva (sialorrhoea) managed in people with motor neurone disease (MND)?

    Recommendation ID NG42/4 Question Saliva:- How is excessive drooling of saliva (sialorrhoea) managed in people with motor neurone disease

    Research recommendation
    Published
    21 March 2016

  11. What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism?

    Recommendation ID NG145/11 Question What is the clinical and cost effectiveness of selenium for people with subclinical hypothyroidism

    Research recommendation
    Published
    10 February 2020

  12. Screening assessment tools:- Develop reliable and valid screening assessment tools for attachment and sensitivity that can be made available and used in routine health, social care and education settings.

    Recommendation ID NG26/1 Question Screening assessment tools:- Develop reliable and valid screening assessment tools for attachment and

    Research recommendation
    Published
    11 December 2015

  13. Self-management:- Do structured psoriasis-focused self-management programmes improve patient confidence, wellbeing and disease control compared with standard care?

    Recommendation ID CG153/4 Question Self-management:- Do structured psoriasis-focused self-management programmes improve patient confidence

    Research recommendation
    Published
    9 June 2015

  14. Further research is recommended on alternative postpartum testing strategies that do not include cord blood typing of all babies born to rhesus-D (D) negative women.

    Recommendation ID DG25/1 Question Further research is recommended on alternative postpartum testing strategies that do not include cord

    Research recommendation
    Published
    10 February 2017

  15. Further research is recommended on clinical outcomes associated with using the ELISA kits (LISA-TRACKER, IDKmonitor and Promonitor) in people whose Crohn's disease is losing response to a TNF-alpha inhibitor. This could be through a prospective study, for local audit, or for submission to a registry. (The IBD Registry is being adapted to receive data on TNF-alpha inhibitor levels and antibodies against TNF-alpha inhibitors).

    Recommendation ID DG22/2 Question Further research is recommended on clinical outcomes associated with using the ELISA kits (LISA-TRACKER

    Research recommendation
    Published
    21 March 2016