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Area of interest

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Type

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Last updated

Guidance programme

Advice programme

Showing 5971 to 5985 of 7712 results

  1. Research is needed to quantify the health outcome benefits associated with imaging improvements with the EOS system. Examples of such benefits might include reduced back pain or reduced postural difficulties in people with scoliosis, or longer lasting and less painful joint replacements. Although research into the use of the EOS system is appropriate for all the indications included in the scope, the research most likely to be useful is for planning hip and knee replacement, including patient selection, device selection, and surgical approach. Joint replacement operations are more common than the other indications and the EOS system is thought to be most likely to provide benefit to these patients.

    Recommendation ID DG1/1 Question Research is needed to quantify the health outcome benefits associated with imaging improvements with the

    Research recommendation
    Published
    9 June 2015

  2. Research is recommended to address uncertainties about the claimed patient and system benefits of the ReCell Spray-On Skin system. Clinical outcomes should include time to 95% healing, length of hospital stay, cosmetic appearance of the scar and function of the burned area, compared with standard care.

    Recommendation ID MTG21/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of the

    Research recommendation
    Published
    9 June 2015

  3. Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination with cardiac troponin testing against sequential cardiac troponin testing for ruling out myocardial infarction.

    Recommendation ID MTG4/1 Question Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination

    Research recommendation
    Published
    9 June 2015

  4. Research is recommended to address uncertainties about the claimed patient and system benefits of using Parafricta Bootees and Undergarments.

    Recommendation ID MTG20/1 Question Research is recommended to address uncertainties about the claimed patient and system benefits of using

    Research recommendation
    Published
    10 August 2021

  5. Research is recommended to address uncertainties in the potential benefits to patients and the NHS of using VibraTip. Research is needed into the diagnostic accuracy of VibraTip compared with the 10 g monofilament and calibrated tuning fork in the diagnosis of peripheral neuropathy in people with diabetes. This research should also address the assessment of vibration perception compared with touch sensation in this clinical context.

    Recommendation ID MTG22/1 Question Research is recommended to address uncertainties in the potential benefits to patients and the NHS of

    Research recommendation
    Published
    9 June 2015

  6. Research on second-line treatments for transitional cell carcinoma of the urothelial tract is needed. It noted that the vinflunine studies were the only studies in patients with transitional cell carcinoma of the urothelial tract whose disease had progressed after platinum-based chemotherapy. It was noted that there is a lack of evidence for the relative effectiveness of treatment options at this stage in the pathway of care. It is recommended that studies be undertaken to investigate the relative safety and efficacy of second-line treatments for transitional cell carcinoma of the urothelial tract, particularly randomised controlled trials.

    Recommendation ID TA272/1 Question Research on second-line treatments for transitional cell carcinoma of the urothelial tract is needed

    Research recommendation
    Published
    9 June 2015

  7. Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears should address patient selection, type of graft and technique used,long-term outcomes including shoulder function, and patient-reported outcome measures.

    Recommendation ID IPG619/1 Question Research on the safety and efficacy of superior capsular augmentation for massive rotator cuff tears

    Research recommendation
    Published
    19 December 2018

  8. Research should be carried out to compare the clinical effectiveness of bendamustine with chlorambucil at the higher dose used in the Chronic Lymphocytic Leukaemia Trial 4 (CLL4).

    Recommendation ID TA216/1 Question Research should be carried out to compare the clinical effectiveness of bendamustine with chlorambucil

    Research recommendation
    Published
    9 June 2015

  9. How often should people with diabetic foot problems (foot ulcers, soft tissue infections, osteomyelitis or gangrene) be reviewed?

    Recommendation ID NG19/8 Question How often should people with diabetic foot problems (foot ulcers, soft tissue infections, osteomyelitis

    Research recommendation
    Published
    18 November 2019

  10. What clinical features and laboratory investigations can be used to better stratify risk for women in labour with signs of sepsis (including fever and tachycardia)?

    Recommendation ID NG121/4 Question What clinical features and laboratory investigations can be used to better stratify risk for women in

    Research recommendation
    Published
    16 August 2019

  11. NICE encourages further research into radiofrequency ablation of the soft palate for snoring. This could take the form of data collection, with the specific aim of documenting long-term outcomes and the need for further treatment.

    Recommendation ID IPG476/1 Question NICE encourages further research into radiofrequency ablation of the soft palate for snoring. This

    Research recommendation
    Published
    9 June 2015

  12. NICE encourages further research on corticosteroid-eluting bioabsorbable stent or spacer insertion during endoscopic sinus surgery and, specifically, controlled studies designed for between-patient (rather than within-patient) comparisons. Outcomes should include symptom scores, quality of life and the need for retreatment in the long term. All complications should be reported. NICE may update this guidance on publication of further evidence.

    Recommendation ID IPG551/1 Question NICE encourages further research on corticosteroid-eluting bioabsorbable stent or spacer insertion

    Research recommendation
    Published
    6 April 2016

  13. NICE encourages further research into endoscopic radiofrequency ablation for Barrett's oesophagus with no dysplasia. Studies should define clearly the policies used for histological diagnosis. Outcomes should include complete resolution of Barrett's oesophagus, change and progression to low-grade dysplasia, high-grade dysplasia or cancer. All complications should be reported, particularly development of strictures. Comparative studies against surveillance would be useful.

    Recommendation ID IPG496/1 Question NICE encourages further research into endoscopic radiofrequency ablation for Barrett's oesophagus with

    Research recommendation
    Published
    9 June 2015

  14. NICE also considered the role of FeNO in guiding inhaled corticosteroid dosing through stepping-up and stepping-down protocols. It accepted there is a need for more evidence on which protocols offer the safest and most optimal asthma management when used in UK clinical practice. Therefore, further studies are recommended, with consideration for the different protocols and cut-off points that may be necessary in different populations.

    Recommendation ID DG12/3 Question NICE also considered the role of FeNO in guiding inhaled corticosteroid dosing through stepping-up and

    Research recommendation
    Published
    9 June 2015

  15. NICE encourages further research into radiofrequency treatment for haemorrhoids, preferably randomised controlled trials. It may update the guidance on publication of further evidence. Outcomes should include pain, secondary haemorrhage, recurrence rate, the need for repeat procedures and quality-of-life measures. Details of patient selection should also be reported.

    Recommendation ID IPG589/1 Question NICE encourages further research into radiofrequency treatment for haemorrhoids, preferably randomised

    Research recommendation
    Published
    15 October 2018