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Medline (1946-present)
Search date: 21st October 2016
1 Glycopyrrolate/ (835)
2 (glycopyrronium or glycopyrrolate or sialanar).tw. (960)
3 1 or 2 (1137)
4 Sialorrhea/ (1184)
5 (drool* or hypersalivat* or sialorrhea).tw. (1708)
6 4 or 5 (2156)
7 3 and 6 (43)
Medline in-process
Search date: 21st October 2016
1 Glycopyrrolate/ (0)
2 (glycopyrronium or glycopyrrolate or sialanar).tw. (99)
3 1 or 2 (99)
4 Sialorrhea/ (0)
5 (drool* or hypersalivat* or sialorrhea).tw. (170)
6 4 or 5 (170)
7 3 and 6 (3)
Embase (1974 to 21th October 2016)
Search date: 21st October 2016
1 Glycopyrrolate/ (5454)
2 (glycopyrronium or glycopyrrolate or sialanar).tw. (1554)
3 1 or 2 (5585)
4 Sialorrhea/ (3973)
5 (drool* or hypersalivat* or sialorrhea).tw. (2723)
6 4 or 5 (5413)
7 3 and 6 (191)
8 limit 7 to English language (177)
9 *randomized controlled trial/ (37703)
10 *Randomization/ (2020)
11 *Placebo/ (55996)
12 *Crossover Procedure/ (3810)
13 (random or randomi* or randoml*).tw. (1137254)
14 rct*.tw. (43365)
15 (phase 4 or phase iv or phase 3 or phase iii).tw. (67806)
16 placebo*.tw. (246741)
17 (crossover* or (cross adj over*)).tw. (85155)
18 9 or 10 or 11 or 12 or 13 or 14 or 15 or 16 or 17 (1319359)
19 Nonhuman/ (4934829)
20 Human/ (17907880)
21 19 not (19 and 20) (3675982)
22 18 not 21 (1216959)
23 Clinical study/ (243890)
24 Case control study/ (121345)
25 Family study/ (24891)
26 Longitudinal study/ (104067)
27 Retrospective study/ (504524)
28 comparative study/ (736482)
29 Prospective study/ (380576)
30 Randomized controlled trials/ (121519)
31 29 not 30 (375968)
32 Cohort analysis/ (294471)
33 cohort analy*.tw. (7596)
34 (Cohort adj (study or studies)).tw. (175045)
35 (Case control* adj (study or studies)).tw. (101756)
36 (follow up adj (study or studies)).tw. (53183)
37 (observational adj (study or studies)).tw. (98943)
38 (epidemiologic* adj (study or studies)).tw. (88348)
39 (cross sectional adj (study or studies)).tw. (128781)
40 case series.tw. (65992)
41 prospective.tw. (618773)
42 retrospective.tw. (562957)
43 or/23-28,31-42 (2923018)
44 22 or 43 (3831639)
45 8 and 44 (39)
Cochrane library databases
Search date: 21st October 2016
#1 MeSH descriptor: [Glycopyrrolate] this term only 245
#2 glycopyrronium or glycopyrrolate or sialanar:ti,ab,kw (Word variations have been searched) 969
#3 #1 or #2 969
#4 MeSH descriptor: [Sialorrhea] this term only 71
#5 drool* or hypersalivat* or sialorrhea:ti,ab,kw (Word variations have been searched) 301
#6 #4 or #5 301
#7 #3 and #6 11