Promoting tolerance of enteral feeds in children and young people: domperidone

Changes after publication

February 2015: Minor maintenance.

September 2014: The following information has become available since this ESUOM was produced:

Domperidone: risks of cardiac side effects - indication restricted to nausea and vomiting, new contraindications, and reduced dose and duration of use.

A European review has confirmed that domperidone is associated with a small increased risk of serious cardiac side effects. Its use is now restricted to the relief of nausea and vomiting and the dosage and duration of use have been reduced. It should no longer be used for the treatment of bloating and heartburn. Domperidone is now contraindicated in those with underlying cardiac conditions and other risk factors. See the Medicines and Healthcare Products Regulatory Agency Drug Safety Update May 2014 for more information.