Advice
Relevance to NICE guidance programmes
Relevance to NICE guidance programmes
Use of metformin for treating PCOS in women who are not planning pregnancy has not been assessed as part of a NICE technology appraisal work programme and is not currently listed as a proposed technology appraisal or an appraisal in development.
Fertility: assessment and treatment for people with fertility problems (NICE clinical guideline 156) recommends women with WHO Group II ovulation disorders or anovulatory infertility should be offered treatment including metformin in certain circumstances.
NICE guidance also exists for the licensed indications for metformin:
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Type 1 diabetes: diagnosis and management of type 1 diabetes in children, young people and adults (NICE clinical guideline 15)
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Type 2 diabetes: the management of type 2 diabetes (NICE clinical guideline 87).
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Diabetes in pregnancy: management of diabetes and its complications from pre-conception to the postnatal period (NICE clinical guideline 63).
NICE is currently updating its guidance on type 1 and type 2 diabetes in children and young people (expected June 2014), diabetes in pregnancy (expected June 2014), type 1 diabetes in adults (expected July 2014), and type 2 diabetes in adults (publication date to be confirmed).