Interventional procedure overview of removal, preservation and reimplantation of ovarian tissue to restore fertility after gonadotoxic treatment
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Indications and current treatment
Some treatments for cancer or other medical conditions can damage the ovaries (gonadotoxic treatment). This can lead to early menopause and infertility.
There are a number of pharmacologic and surgical strategies that aim to reduce the risk of infertility after gonadotoxic treatment, including ovarian transposition, ovarian suppression, and fertility-sparing surgery.
Cryopreservation of oocytes or embryos before starting treatment are options for women who wish to preserve their fertility. These both involve ovarian stimulation, which may lead to a delay in treatment. For embryo cryopreservation there is also a need for sperm from either a partner or sperm donor.
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