How are you taking part in this consultation?

You will not be able to change how you comment later.

You must be signed in to answer questions

    The content on this page is not current guidance and is only for the purposes of the consultation process.

    Methods

    NICE identified studies and reviews relevant to minimally invasive fusionless posterior-approach surgery to correct idiopathic scoliosis in children and young people from the medical literature. The following databases were searched between the date they started to 21.07.2022: MEDLINE, PREMEDLINE, EMBASE, Cochrane Library and other databases. Trial registries and the internet were also searched (see the literature search strategy). Relevant published studies identified during consultation or resolution that are published after this date may also be considered for inclusion.

    The following inclusion criteria were applied to the abstracts identified by the literature search.

    • Publication type: clinical studies were included with emphasis on identifying good quality studies. Abstracts were excluded if they did not report clinical outcomes. Reviews, editorials, and laboratory or animal studies, were also excluded and so were conference abstracts, because of the difficulty of appraising study methodology, unless they reported specific adverse events that not available in the published literature.

    • Patients with adolescent idiopathic scoliosis.

    • Intervention or test: minimally invasive fusionless deformity correction surgery.

    • Outcome: articles were retrieved if the abstract contained information relevant to the safety, efficacy, or both.

    If selection criteria could not be determined from the abstracts the full paper was retrieved.

    Potentially relevant studies not included in the main evidence summary are listed in the section on other relevant studies.

    Find out more about how NICE selects the evidence for the committee.

    Table 4 literature search strategy

    Databases

    Date searched

    Version/files

    MEDLINE (Ovid)

    21/07/2022

    1946 to July 20, 2022

    MEDLINE In-Process (Ovid)

    21/07/2022

    1946 to July 20, 2022

    MEDLINE Epubs ahead of print (Ovid)

    21/07/2022

    July 20, 2022

    EMBASE (Ovid)

    21/07/2022

    1974 to July 20, 2022

    EMBASE Conference (Ovid)

    21/07/2022

    1974 to July 20, 2022

    Cochrane Database of Systematic Reviews – CDSR (Cochrane Library)

    21/07/2022

    Issue 7 of 12, July 2022

    Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library)

    21/07/2022

    Issue 7 of 12, July 2022

    International HTA database (INAHTA)

    21/07/2022

    -

    The following search strategy was used to identify papers in MEDLINE. A similar strategy was used to identify papers in other databases.

    MEDLINE search strategy

    The MEDLINE search strategy was translated for use in the other sources.

    1 Scoliosis/ 20124

    2 scoliosis.tw. 19986

    3 (Skeletal* adj4 immatur*).tw. 1864

    4 or/1-3 26245

    5 (Self adj4 adjust* adj4 rod*).tw. 0

    6 (Fusionless or (Non adj4 fusion*)).tw,kw. 1669

    7 (Deform* adj4 correct* adj4 (surger* or device* or system*)).tw. 754

    8 ((Posterior adj4 dynamic adj4 deformity adj4 correction) or PDDC).tw,kw. 22

    9 (motion adj4 sparing adj4 posterior adj4 device).tw. 1

    10 or/5-9 2437

    11 4 and 10 347

    12 ((Minimally adj4 Invasive adj4 Deformity adj4 Correction adj4 system) or MIDCS).tw. 1

    13 (MID-C adj4 (correction or system)).tw. 1

    14 ApiFix.tw. 3

    15 or/11-14 348

    16 Animals/ not Humans/ 5004195

    17 15 not 16 305