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    Literature search strategy

    Databases

    Date searched

    Version/files

    Cochrane Database of Systematic Reviews – CDSR (Cochrane)

    22/12/2021

    Issue 12 of 12, December 2021

    Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane)

    22/12/2021

    Issue 12 of 12, December 2021

    International HTA database (INAHTA)

    22/12/2021

    -

    MEDLINE (Ovid)

    22/12/2021

    1946 to December 21, 2021

    MEDLINE In-Process (Ovid)

    22/12/2021

    1946 to December 21, 2021

    MEDLINE Epubs ahead of print (Ovid)

    22/12/2021

    1946 to December 21, 2021

    EMBASE (Ovid)

    22/12/2021

    1974 to 2021 December 21

    EMBASE Conference (Ovid)

    22/12/2021

    1974 to 2021 December 21

    Trial sources searched

    • Clinicaltrials.gov

    • ISRCTN

    • WHO International Clinical Trials Registry

    Websites searched

    • National Institute for Health and Care Excellence (NICE)

    • NHS England

    • Food and Drug Administration (FDA) - MAUDE database

    • Australian Safety and Efficacy Register of New Interventional Procedures – Surgical (ASERNIP – S)

    • Australia and New Zealand Horizon Scanning Network (ANZHSN)

    • General internet search

    The following search strategy was used to identify papers in MEDLINE. A similar

    strategy was used to identify papers in other databases.

    Literature search strategy

    Number

    Search term

    1

    Thyroid Nodule/

    2

    Thyroid Diseases/

    3

    (Thyroid* adj4 (nodul* or adenom* or cyst* or diseas* or lump* or tumor* or tumour*)).tw.

    4

    AFTN.tw.

    5

    BTNs.tw.

    6

    exp Goiter/

    7

    (goitre* or goiter*).tw.

    8

    or/1-7

    9

    (benign or benignant or harmless or non-malignant or non-cancerous).tw.

    10

    8 and 9

    11

    Radiofrequency Ablation/

    12

    Catheter Ablation/

    13

    ((radiofrequen* or radio-frequen* or radio frequen* or rf) adj4 ablat*).tw.

    14

    (Radio* adj4 frequen* adj4 ablat*).tw.

    15

    RFA.tw.

    16

    ((catheter* or needle* or electrode* or heat* or (transvenous adj1 electric*)) adj4 ablat*).tw.

    17

    Ablation Techniques/

    18

    (percutan* adj4 ablat*).tw.

    19

    Microwaves/

    20

    MWA.tw.

    21

    (Microwave* adj4 ablat*).tw.

    22

    ultrasound guided.tw.

    23

    or/11-22

    24

    10 and 23

    25

    TATO.tw.

    26

    Thermal Ablation Treatments for Oncology.tw.

    27

    25 or 26

    28

    24 or 27

    29

    animals/ not humans/

    30

    28 not 29