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2 Information about sebelipase alfa

Marketing authorisation indication

2.1 Sebelipase alfa (Kanuma, Alexion) is indicated for 'long-term enzyme replacement therapy (ERT) in patients of all ages with lysosomal acid lipase (LAL) deficiency'.

Dosage in the marketing authorisation

2.2 The dosage schedule is available in the summary of product characteristics for sebelipase alfa.

Price

2.3 The list price of sebelipase alfa is £6,286 for a 20 mg vial (excluding VAT; company submission).

2.4 The company has a commercial arrangement, which would have applied if sebelipase alfa had been recommended.