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    The content on this page is not current guidance and is only for the purposes of the consultation process.

    Unmet need

    Most people with CCHS need lifelong ventilatory support using a mechanical ventilator. Most of them only need support during sleep and some also need daytime assistance with breathing. While some people will remain ventilated by MV, many people may benefit from PNP, especially older children and adults who have hidden daytime hypoventilation. PNP allows breathing without the need for a tracheostomy or mask ventilation, maintaining mobility and potentially improving quality of life.