Interventional procedure overview of laparoscopic insertion of an inactive implant for gastro-oesophageal reflux disease
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Unmet need
GORD is usually a chronic condition that affects between 10% and 30% of people in developed countries. In England, according to Hospital Episode Statistics (admitted patient care), there were approximately 98,102 finished consultant episodes for people with a primary diagnosis of GORD in 2022 to 2023.
Unlike other options, this procedure does not involve implanting materials in the LOS or a full fundoplication around the LOS. This may be beneficial because encircling or implanting materials into the LOS can lead to side effects such as swallowing difficulties (dysphagia), painful swallowing (odynophagia) and inability to vomit or belch, which impact quality of life.
This procedure could provide a minimally invasive option for people with chronic GORD whose symptoms have not responded adequately to lifestyle modification and drug therapy. There are also limited treatment options for those with more complex cases, such as those with oesophageal dysmotility (such as IOM disorders), larger HH or preoperative dysphagia. This is because people in this group may have a higher risk of postoperative dysphagia, so are often treated more conservatively.
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