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    References

    1. Van Hoof L, Rega F, Golesworthy T et al. (2021) Personalised external aortic root support for elective treatment of aortic root dilation in 200 patients. Heart doi: 10.1136/heartjnl-2021-319300

    2. Pepper J, Golesworthy TJ, Izgi C et al. (2020) Personalised external aortic root support (PEARS) to stabilise an aortic root aneurysm. British Journal of Cardiology 27: 87–92

    3. Treasure T, Takkenberg JJM, Golesworthy T et al. (2014) Personalised external aortic root support (PEARS) in Marfan syndrome: analysis of 1‑9 year outcomes by intention-to-treat in a cohort of the first 30 consecutive patients to receive a novel tissue and valve-conserving procedure, compared with the published results of aortic root replacement. Heart (British Cardiac Society) 100: 969–75

    4. Izgi C, Newsome S, Alpendurada F et al. (2018) External aortic root support to prevent aortic dilatation in patients with Marfan syndrome. Journal of the American College of Cardiology 72: 1095–105

    5. Treasure T, Crowe S, John Chan KM et al. (2012) A method for early evaluation of a recently introduced technology by deriving a comparative group from existing clinical data: A case study in external support of the Marfan aortic root. BMJ Open 2: a1

    6. Pepper J, Goddard M, Mohiaddin R et al. (2015) Histology of a Marfan aorta 4.5 years after personalized external aortic root support. European Journal of Cardio-thoracic Surgery 48: 502–5

    7. Kockova R, Maly J, Krebsova A et al. (2019) Inflammatory response after ExoVasc personalized external aortic root support (PEARS) procedure in patients with Marfan syndrome or non-Marfan genetic aortopathy. European Heart Journal 40 (no. supplement1): 3482

    8. Nemec P, Fila P, Pepper J (2020) Personalized external aortic root support. Interactive Cardiovascular and Thoracic Surgery 31: 342–5

    9. Benedetto U, Melina G, Takkenberg JJ, et al. (2011) Surgical management of aortic root disease in Marfan syndrome: a systematic review and meta-analysis. Heart 97:955–8