Interventional procedure overview of intraoperative electron beam radiotherapy for locally advanced and locally recurrent colorectal cancer
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What the procedure involves
The procedure is done during surgery for locally advanced or locally recurrent colorectal cancer. Once the tumour is resected, the patient is positioned to receive a megavoltage electron dose from a linear accelerator. Either the operating theatre is equipped with a stationary linear accelerator, the patient is transferred to a dedicated room, or a mobile linear accelerator is brought into the theatre. Radiation-sensitive organs surrounding the tumour site can be displaced or shielded from the IOERT field. A single large fraction of radiation (typically 10 to 20 Gy) is then delivered via an applicator directly to the tumour bed. The aim is to improve local control and increase survival rates.
There are several techniques for delivering IORT, including IOERT, HDR-brachytherapy, and orthovoltage. This overview is a summary of the evidence for IOERT and is not an assessment of HDR-brachytherapy or orthovoltage techniques.
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