Interventional procedure overview of endoscopic duodenal mucosal resurfacing for insulin resistance in type 2 diabetes
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Methods
NICE identified studies and reviews relevant to endoscopic DMR for insulin resistance in T2D from the medical literature. The following databases were searched between the date they started to 22/03/2023: MEDLINE, PREMEDLINE, EMBASE, Cochrane Library and other databases. Trial registries and the internet were also searched (see the literature search strategy). Relevant published studies identified during consultation or resolution that are published after this date may also be considered for inclusion.
The following inclusion criteria were applied to the abstracts identified by the literature search.
Publication type: clinical studies were included with emphasis on identifying good quality studies. Abstracts were excluded if they did not report clinical outcomes. Reviews, editorials, and laboratory or animal studies, were also excluded and so were conference abstracts, because of the difficulty of appraising study methodology, unless they reported specific AEs that are not available in the published literature.
Patients with type 2 diabetes.
Intervention or test: duodenal mucosal resurfacing.
Outcome: articles were retrieved if the abstract contained information relevant to the safety, efficacy, or both.
If selection criteria could not be determined from the abstracts the full paper was retrieved.
Potentially relevant studies not included in the main evidence summary are listed in the section on other relevant studies.
Find out more about how NICE selects the evidence for the committee.
Databases | Date searched | Version/files |
MEDLINE (Ovid) | 22/03/2023 | 1946 to March 21, 2023 |
MEDLINE In-Process (Ovid) | 22/03/2023 | 1946 to March 21, 2023 |
MEDLINE Epubs ahead of print (Ovid) | 22/03/2023 | March 21, 2023 |
EMBASE (Ovid) | 22/03/2023 | 1974 to March 21, 2023 |
EMBASE Conference (Ovid) | 22/03/2023 | 1974 to March 21, 2023 |
Cochrane Database of Systematic Reviews – CDSR (Cochrane Library) | 22/03/2023 | |
Cochrane Central Database of Controlled Trials – CENTRAL (Cochrane Library) | 22/03/2023 | Issue 2 of 12, February 2023 |
International HTA database (INAHTA) | 22/03/2023 | Issue 3 of 12, March 2023 |
The following search strategy was used to identify papers in MEDLINE. A similar strategy was used to identify papers in other databases.
The MEDLINE search strategy was translated for use in the other sources.
1 Diabetes Mellitus, Type 2/ 167595
2 ((diabet* or DM) adj4 ("type 2" or type2 or "type ii" or "type two" or T2 or T-2 or TII or T-II)).ti,ab. 156433
3 (dm2 or t2d* or mody or niddm).ti,ab. 46927
4 (DM adj4 (keto* or acidi* or gastropare*)).ti,ab. 86
5 ((DM adj4 onset* adj4 (maturit* or adult* or slow*)) or (DM adj4 depend* adj4 (non-insulin* or non insulin* or noninsulin*))).ti,ab. 171
6 or/1-5 207060
7 Intestinal Mucosa/ 93821
8 Duodenum/ 38708
9 7 and 8 5575
10 (duodenal adj4 mucosa*).tw. 3996
11 ((gastric adj4 epithelium) or (gastric adj4 surface adj4 epithelial adj4 metaplasia)).tw. 2161
12 (Duoden* adj4 dysfunct*).tw. 67
13 Insulin Resistance/ 66545
14 (insulin adj4 (sensitiv* or resist*)).tw. 106448
15 6 or 9 or 10 or 11 or 12 or 13 or 14 297290
16 Ablation Techniques/ 3426
17 (((Duoden* or hydrothermal or water) adj4 (resurfac* or ablati*)) or DMR).tw. 1806
18 (thermal adj4 (energy or ablat* or resurfac*)).tw. 7271
19 (organ adj4 edit*).tw. 49
20 (balloon adj4 catheter).tw. and endoscopes/ 49
21 ((balloon adj4 catheter) and endoscop*).tw. 584
22 or/16-21 12622
23 15 and 22 68
24 Revita.tw. 3
25 23 or 24 69
26 Animals/ not Humans/ 5071443
27 25 not 26 62
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