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    Interventional procedure overview of endoscopic duodenal mucosal resurfacing for insulin resistance in type 2 diabetes

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    What the procedure involves

    Endoscopic DMR is a minimally invasive procedure. It involves endoscopic exploration under general anaesthesia or deep sedation. This is followed by submucosal expansion with saline, and then hydrothermal ablation of the duodenal mucosa under direct vision with fluoroscopic guidance. The aim is for mucosal regeneration, and so to treat the duodenal dysfunction that is thought to contribute to insulin resistance.