Evidence | Depression in adults: treatment and management | Guidance | NICE

Evidence

Review and download supporting evidence. Includes the full guideline if available.

Supporting evidence

Evidence review
Evidence reviews
A: Service delivery ^{PDF 5.37 MB} 29 June 2022
B: Treatment of a new episode of depression ^{PDF 20.31 MB} 29 June 2022
C: Preventing relapse ^{PDF 4.23 MB} 29 June 2022
D: Further-line treatment ^{PDF 8.25 MB} 29 June 2022
E: Chronic depression ^{PDF 3.01 MB} 29 June 2022
F: Depression with coexisting personality disorder ^{PDF 1.17 MB} 29 June 2022
G: Psychotic depression ^{PDF 1.04 MB} 29 June 2022
H: Access to services ^{PDF 1.09 MB} 29 June 2022
I: Patient Choice ^{PDF 1.73 MB} 29 June 2022
A1: Clinical evidence tables for review question 1.1 ^{Excel 197 KB} 29 June 2022
A2: Clinical evidence tables for review question 1.2 ^{Excel 294 KB} 29 June 2022
B1: Clinical evidence tables for review questions 2.1-2.2 ^{Excel 2.58 MB} 29 June 2022
B2: Forest plots for treatment of a new episode of less severe depression ^{PDF 3.84 MB} 29 June 2022
B3: Forest plots for first-line treatment of more severe depression ^{PDF 8.95 MB} 29 June 2022
B4: Pairwise and NMA comparisons for review questions 2.1-2.2 ^{Excel 26 KB} 29 June 2022
C1: Clinical evidence tables for review question 2.3 ^{Excel 718 KB} 29 June 2022
D1: Clinical evidence tables for review question 2.4-2.5 ^{Excel 5.53 MB} 29 June 2022
E1: Clinical evidence tables for review question 2.6 ^{Excel 247 KB} 29 June 2022
F1: Clinical evidence tables for review question 2.7 ^{Excel 90 KB} 29 June 2022
G1: Clinical evidence tables for review question 2.8 ^{Excel 78 KB} 29 June 2022
H1: Clinical evidence tables for review question 3.0 ^{Excel 45 KB} 29 June 2022
I1: Clinical evidence tables for review question 4.0 ^{Excel 189 KB} 29 June 2022
Other supporting evidence
Appendices 1 and 2 (recommendations that have been deleted, or changed without an evidence review) ^{PDF 152 KB} 29 June 2022
Supplement 2: Glossary and abbreviations ^{PDF 375 KB} 29 June 2022
Supplement 1: Methods ^{PDF 359 KB} 29 June 2022
Economic evidence ^{Excel 52 KB} 29 June 2022
Full guidance
Full guideline - October 2009 ^{PDF 3.7 MB} 29 June 2022
Full guidance, appendix 15 ^{PDF 419 KB} 25 August 2010
Full guidance, appendix 16a ^{PDF 394 KB} 25 August 2010
Full guidance, appendix 16b ^{PDF 2.35 MB} 25 August 2010
Full guidance, appendix 16c ^{PDF 2.78 MB} 25 August 2010
Full guidance, appendix 16d ^{PDF 707 KB} 25 August 2010
Full guidance, appendix 17a ^{PDF 806 KB} 25 August 2010
Full guidance, appendix 17b ^{PDF 1.68 MB} 25 August 2010
Full guidance, appendix 17c ^{PDF 8.94 MB} 25 August 2010
Full guidance, appendix 17d ^{PDF 433 KB} 25 August 2010
Full guidance, appendix 18 ^{PDF 1.12 MB} 25 August 2010
Full guidance, appendix 19a ^{PDF 367 KB} 25 August 2010
Full guidance, appendix 19b ^{PDF 3.79 MB} 25 August 2010
Full guidance, appendix 19c ^{PDF 6.05 MB} 25 August 2010
Full guidance, appendix 19d ^{PDF 354 KB} 25 August 2010
Full guidance, appendix 20 ^{PDF 831 KB} 25 August 2010
Full guidance, appendix 21 ^{PDF 313 KB} 25 August 2010