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    Interventional procedure overview of single-step scaffold insertion for repairing symptomatic chondral knee defects

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    References

    1. Migliorini F, Maffulli N, Baroncini A et al. (2022a) Autologous matrix‑induced chondrogenesis is effective for focal chondral defects of the knee. Scientific Reports 12: 9328

    2. Kim JH, Heo JW, Lee DH (2020a) Clinical and radiological outcomes after autologous matrix-induced chondrogenesis versus microfracture of the knee. A systematic review and meta-analysis with a minimum 2-year follow-up. The Orthopaedic Journal of Sports Medicine 8: 2325967120959280

    3. Migliorini F, Eschweiler J, Götze C et al. (2022b) Matrix- induced autologous chondrocyte implantation (mACI) versus autologous matrix-induced chondrogenesis (AMIC) for chondral defects of the knee: a systematic review. British Medical Bulletin 141: 47-59

    4. Migliorini F, Eschweiler J, Schenker H et al. (2021a) Surgical management of focal chondral defects of the knee: a Bayesian network meta-analysis. Journal of Orthopaedic Surgery and Research 16: 543

    5. Tan CHB, Huang XYO, Tay ZQ et al. (2023) Arthroscopic and open approaches for autologous matrix-induced chondrogenesis repair of the knee have similar results: a meta-analysis. Journal of ISAKOS: In press.

    6. da Cunha CB, Andrade R, Veloso TR et al. (2020) Enhanced microfracture using acellular scaffolds improves results after treatment of symptomatic focal grade III/IV knee cartilage lesions but current clinical evidence does not allow unequivocal recommendation. Knee Surgery, Sports Traumatology, Arthroscopy 28: 3245-57

    7. Altschuler N, Zaslav, KR, Matteo B et al. (2023) Aragonite-based scaffold versus microfracture and debridement for the treatment of knee chondral and osteochondral lesions: Results of a multicenter randomized controlled trial. The American Journal of Sports Medicine 51: 957-967

    8. Kim MS, Chun CH, Wang JH et al. (2020b) Microfractures versus a porcine-derived collagen-augmented chondrogenesis technique for treating knee cartilage defects: A multicenter randomized controlled trial. Arthroscopy: The Journal of Arthroscopic and Related Surgery 36: 1612-1624

    9. Kon E, Filardo G, Brittberg M, et al. (2018) A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years. Knee Surg Sports Traumatol Arthrosc.26: 2704- 2715

    10. Shive MS, Stanish WD, McCormack R et al. (2015) BSTCarGel® treatment maintains cartilage repair superiority over microfracture at 5 years in a multicenter randomized controlled trial. Cartilage 6:62–72

    11. Gille J, Reiss E, Freitag M et al. (2021) Autologous matrix-induced chondrogenesis for treatment of focal cartilage defects in the knee: a follow up study. The Orthopaedic Journal of Sports Medicine 9: 2325967120981872

    12. de Girolamo L, Schonhuber H, Vigano M, et al. (2019) Autologous matrix-induced chondrogenesis (AMIC) and AMIC enhanced by autologous concentrated bone marrow aspirate (BMAC) allow for stable clinical and functional improvements at up to 9 years follow-up: Results from a randomized controlled study. Journal of Clinical Medicine 8: 392