Interventional procedure overview of single-step scaffold insertion for repairing symptomatic chondral knee defects

What the procedure involves

In this procedure, a scaffold is put into the area of damaged cartilage to encourage cells to grow into new cartilage. This is a single-step procedure because the cells are not cultured outside the body. A range of techniques can be used to introduce the cells that grow into new cartilage, supported by the scaffold. For example, tiny holes can be drilled into the bone (microfracture) to release the cells, or substances like bone marrow aspirate can be put into the area of damage. Whichever method is done, it is always done in the same operation as the scaffold insertion.

There are different types of scaffold and ways of doing the procedure. For example, some scaffolds are solid and some are injectable gels. Some of the solid scaffolds must be cut to size and applied over the defect. Other scaffolds are a standard size and shape, and are implanted into the subchondral bone in the damaged area. The procedure aims to repair the damaged cartilage, reduce symptoms and keep the joint working.