Interventional procedure overview of single-step scaffold insertion for repairing symptomatic chondral knee defects
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Unmet need
Damage to articular cartilage is common and unlikely to heal spontaneously because the cartilage does not have a blood supply. Surgical options like microfracture can be done in 1 procedure but are designed for small lesions. Options like ACI and mACI are designed for bigger lesions but need 2 procedures a few weeks apart because cells need to be extracted and cultured before being implanted. Scaffold insertion without cultured cell implantation has the potential advantage of being a single-step procedure and may be better for larger lesions than microfracture alone.
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